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LODERX BLOG

Guides, research, and straight talk.

What clinicians actually know about peptide therapy, GLP-1s, and TRT — written for patients, reviewed by physicians.

What Does "Compounded" Mean for GLP-1 Medications? A Plain-Language Guide
glp-1

What Does "Compounded" Mean for GLP-1 Medications? A Plain-Language Guide

A plain-language breakdown of what compounded means for GLP-1 medications, how it differs from FDA-approved brand drugs, and the pharmacy pathway behind it.

September 15, 2026
Estradiol on TRT: Why Clinicians Monitor It and What the Levels Mean
trt

Estradiol on TRT: Why Clinicians Monitor It and What the Levels Mean

Why estradiol matters on testosterone therapy, what reference ranges clinicians use, and how monitoring guides dose adjustments over time.

September 13, 2026
TB-500: What Patients Should Know Before Asking a Clinician About It
peptides

TB-500: What Patients Should Know Before Asking a Clinician About It

TB-500 is a compounded peptide, not an FDA-approved drug. Learn what research shows, who should avoid it, and what to ask a clinician before requesting it.

September 12, 2026
TRT Dosing Frameworks: How Clinicians Start and Adjust Therapy
trt

TRT Dosing Frameworks: How Clinicians Start and Adjust Therapy

How clinicians choose a starting TRT dose, when they adjust it, and which labs guide the decision. A framework overview, not individual medical advice.

September 11, 2026
Low Testosterone vs. Normal Aging: How Clinicians Tell the Difference
trt

Low Testosterone vs. Normal Aging: How Clinicians Tell the Difference

Fatigue and low libido can mean normal aging or low testosterone. Learn the two-part clinical standard doctors use to tell them apart.

September 10, 2026
TRT Ancillary Medications: What Anastrozole and hCG Are For
trt

TRT Ancillary Medications: What Anastrozole and hCG Are For

Anastrozole and hCG are sometimes added to TRT protocols for specific reasons. Here's what each medication does, who might need one, and who doesn't.

September 10, 2026
Who Qualifies for TRT? The Candidacy Criteria Clinicians Actually Use
trt

Who Qualifies for TRT? The Candidacy Criteria Clinicians Actually Use

Who actually qualifies for TRT? See the testosterone cutoffs, symptom criteria, and bloodwork guidelines from AUA, Endocrine Society, and ACP.

September 9, 2026
Cold Exposure and Longevity: What the Research Supports and What Remains Unproven
longevity

Cold Exposure and Longevity: What the Research Supports and What Remains Unproven

Cold plunges are trending in longevity circles. Here's what peer-reviewed research actually shows about cold exposure, inflammation, and lifespan.

September 8, 2026
Alcohol and Longevity: What the Current Evidence Really Shows
alcohol

Alcohol and Longevity: What the Current Evidence Really Shows

Moderate drinking and lifespan: what recent cohort studies, Harvard, Stanford, and CDC data actually say, and how it fits a longevity plan.

September 7, 2026
Continuous Glucose Monitors For Longevity: What The Evidence Shows In Non-Diabetics
cgm

Continuous Glucose Monitors For Longevity: What The Evidence Shows In Non-Diabetics

CGMs are marketed for longevity, but what does research actually show in people without diabetes? A look at the evidence, gaps, and where glucose fits into bloodwork.

September 5, 2026
Fasting vs. Non-Fasting Labs: What Actually Changes on a Men's Health Panel
bloodwork

Fasting vs. Non-Fasting Labs: What Actually Changes on a Men's Health Panel

Does fasting change testosterone, lipids, or glucose results? A breakdown of which men's health panel markers fasting actually affects, and which it doesn't.

September 4, 2026
Peptide Research Ethics: Why Research-Only Framing Protects Patients
peptides

Peptide Research Ethics: Why Research-Only Framing Protects Patients

Why credible peptide providers use research-only framing, what it protects patients from, and how compliant clinical pathways differ from RUO sellers.

September 3, 2026