Guides, research, and straight talk.

Compounded GLP-1 Maintenance Dosing: What Happens After the Loading Phase

What changes when GLP-1 treatment moves from loading to maintenance dosing, how clinicians decide on dose, and what monitoring looks like going forward.

October 2, 2026

GLP-1 Nausea During Titration: What Clinicians Recommend

Nausea is the most common GLP-1 side effect during dose titration. Here is what clinicians recommend for eating, pacing, and when to call for help.

October 1, 2026

GLP-1 and Muscle Loss: What the Research Says About Preserving Lean Mass

GLP-1 medications can reduce lean mass along with fat. Here's what 2026 research shows about protecting muscle through training, protein, and monitoring.

October 1, 2026

Compounded Tirzepatide Shortage Rules in 2026: What Changed and What Stayed the Same

FDA removed tirzepatide from its shortage list in late 2024. Here is what that meant for compounded tirzepatide access heading into 2026, and what did not change.

September 30, 2026

Compounded Testosterone vs. Commercial Formulations: What the Regulatory Pathway Actually Means

Compounded testosterone and commercial testosterone travel different regulatory paths. Here is what FDA oversight, 503A rules, and quality checks actually mean for TRT patients.

September 29, 2026

nutrition

Magnesium and Zinc for Men's Health: What the Evidence Actually Supports

A look at what peer-reviewed research says about magnesium and zinc for testosterone, sleep, and recovery in men, and where the evidence stops.

September 27, 2026

TRT and Fertility: What Clinicians Discuss Before Starting Therapy

TRT can suppress sperm production. Learn what clinicians ask about fertility goals, sperm banking, and alternatives before starting testosterone therapy.

TRT Lab Retest Timing: How Often Clinicians Recheck Levels in the First Year

How often are TRT labs rechecked in year one? A breakdown of the 6-week, 3-month, 6-month, and 12-month retest cadence clinicians use, and why dose changes reset it.

Primary vs Secondary Hypogonadism: How Clinicians Distinguish the Causes of Low Testosterone

Low testosterone has two distinct origins. Learn how LH and FSH labs separate primary from secondary hypogonadism and why the distinction changes care.

TRT and Liver Function: What Clinicians Monitor and Why

Learn which liver labs clinicians order during TRT, why ALT and AST matter, and what abnormal results can mean for testosterone therapy candidates.