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LODERX BLOG

Guides, research, and straight talk.

What clinicians actually know about peptide therapy, GLP-1s, and TRT — written for patients, reviewed by physicians.

Taper vs. Stop: How Clinicians Plan an Off-Ramp From Compounded GLP-1 Therapy
glp-1

Taper vs. Stop: How Clinicians Plan an Off-Ramp From Compounded GLP-1 Therapy

Stopping a compounded GLP-1 isn't a single decision. Here's how clinicians weigh tapering versus stopping, what monitoring looks like, and what to expect.

September 3, 2026
Sermorelin vs Ipamorelin: How Clinicians Frame the Research Differences
peptides

Sermorelin vs Ipamorelin: How Clinicians Frame the Research Differences

Sermorelin and ipamorelin work through different receptors. Here is how clinicians compare the research, safety signals, and regulatory status of each.

September 2, 2026
Peptide Sourcing Red Flags: What Separates a 503A Pathway from Gray-Market Vendors
peptides

Peptide Sourcing Red Flags: What Separates a 503A Pathway from Gray-Market Vendors

Learn the concrete differences between a 503A compounding pathway and gray-market peptide vendors, plus the red flags that signal unsafe sourcing.

September 1, 2026
Side Effects of Compounded GLP-1s: Nausea, GI Symptoms, and What Patients Report
glp-1

Side Effects of Compounded GLP-1s: Nausea, GI Symptoms, and What Patients Report

Nausea and GI symptoms are the most reported side effects of GLP-1 medications. Learn why they happen, how long they last, and when to call a clinician.

August 29, 2026
Compounded GLP-1s and Gallbladder Risk: What the Research Shows
glp-1

Compounded GLP-1s and Gallbladder Risk: What the Research Shows

A look at the peer-reviewed evidence on GLP-1 receptor agonists and gallbladder disease, what it means for compounded semaglutide and tirzepatide, and warning signs to watch.

August 28, 2026
GLP-1 Injection Anxiety: Practical Tips Clinicians Share for First-Time Patients
glp-1

GLP-1 Injection Anxiety: Practical Tips Clinicians Share for First-Time Patients

Nervous about your first GLP-1 shot? Clinician-informed, source-backed tips to lower injection anxiety, ease nerves, and know when to call your provider.

August 27, 2026
What to Expect in Your First Compounded GLP-1 Telehealth Consultation
glp-1

What to Expect in Your First Compounded GLP-1 Telehealth Consultation

A walkthrough of what actually happens in a first compounded GLP-1 telehealth visit: intake, clinician review, candidacy screening, and what comes after.

August 27, 2026
Hematocrit and TRT: Why Clinicians Monitor Red Blood Cell Counts
trt

Hematocrit and TRT: Why Clinicians Monitor Red Blood Cell Counts

Why does testosterone therapy raise hematocrit? Learn the mechanism, safe thresholds, symptoms of erythrocytosis, and how clinicians monitor labs on TRT.

August 26, 2026
PSA Testing on TRT: What Clinicians Monitor and Why
trt

PSA Testing on TRT: What Clinicians Monitor and Why

Why PSA testing matters on TRT, how often clinicians check it, and what a rising PSA level means for men on testosterone therapy.

August 25, 2026
TRT and Blood Pressure: What Clinicians Monitor During Treatment
trt

TRT and Blood Pressure: What Clinicians Monitor During Treatment

TRT can modestly raise blood pressure, mainly through increased hematocrit. Learn what clinicians check before and during testosterone therapy.

August 24, 2026
TRT and Sleep Apnea: What Clinicians Screen For Before Prescribing
trt

TRT and Sleep Apnea: What Clinicians Screen For Before Prescribing

Learn why clinicians screen for obstructive sleep apnea before prescribing TRT, which tools they use, and what red flags can delay or redirect treatment.

August 24, 2026
TRT Plateau: Why Testosterone Levels Stall and What Clinicians Adjust
trt

TRT Plateau: Why Testosterone Levels Stall and What Clinicians Adjust

Testosterone levels stalling on TRT? Learn the lab-confirmed reasons for a plateau and the specific adjustments clinicians consider before changing protocol.

August 24, 2026